Nervalin 25mg Capsule 10pcs

Uses of Nervalin 25

Stop taking Nervalin 25 and seek immediate medical attention if you experience any of the following severe side effects:

• Serious skin reactions involving reddish non-elevated patches on the trunk, often with blisters, skin peeling, and ulcers in the mouth, throat, nose, genitals, or eyes (Stevens-Johnson syndrome, toxic epidermal necrolysis)
• Yellowing of the skin and eyes (jaundice)
• Suicidal thoughts

Nervalin 25 is used in adults to treat:

• Peripheral and central neuropathic pain
• Epilepsy (fits or seizures) in combination with other medicines
• Generalized Anxiety Disorder

How does Nervalin 25 work?

The medication's mechanism of action involves its role as an analog of the neurotransmitter GABA, binding to the alpha2-delta subunit to modulate calcium channels and reduce the release of various neurotransmitters. This modulation helps alleviate abnormal electrical activity in the brain, reducing seizures and interferes with pain signals in damaged nerves, thereby relieving nerve pain. Additionally, it may help alleviate anxiety symptoms by inhibiting the release of certain neurotransmitters associated with anxiety.

Side Effects of Nervalin 25

Common:

• Dizziness, drowsiness, headache
• Increased appetite
• Heightened mood, confusion, disorientation, irritability
• Lack of attention, clumsiness, memory impairment
• Tremor, difficulty in speaking
• Tingling or numbness, sedation, lethargy
• Difficulty in sleeping, tiredness
• Blurred vision, double vision
• A sensation of spinning, balance problems
• Dry mouth, constipation, vomiting, flatulence, diarrhea, nausea, abdominal swelling
• Swelling in extremities (hands, legs, or fingers)
• Feeling intoxicated, abnormal gait
• Weight gain
• Muscle cramps, joint or back pain, limb pain
• Sore throat
• Erectile difficulties, decreased libido, delayed ejaculation

Uncommon:

• Loss of appetite, weight loss
• High or low blood sugar levels
• Hallucinations, mood swings
• Dry eyes, eye pain, watery eyes, eye swelling
• Heart rate irregularities, high or low blood pressure
• Flushing
• Breathing difficulties, dry nose, nasal congestion
• Increased salivation, heartburn, numbness around the mouth
• Sweating, rash, chills, fever
• Breast pain
• Painful menstruation
• Cold hands and feet

Rare:

• Abnormal sense of smell
• Cold sweat, throat tightness, tongue swelling
• Pancreatitis
• Difficulty with proper writing
• Pulmonary fluid accumulation
• Muscle damage
• Breast discharge, abnormal breast growth in males
• Reduced urine output
• Signs of Parkinsonism (muscle stiffness, tremors, decreased mobility)

Quick Suggestions:

• Nervalin 25 is a medication utilized to alleviate pain stemming from nerve damage, known as neuropathic pain, associated with conditions such as diabetes, shingles (herpes zoster infection), and spinal cord injury, among others.
• It also serves as a treatment for widespread muscle pain and stiffness in individuals with fibromyalgia.
• Belonging to the anti-epileptic drug class, Nervalin 25 is effective in managing certain types of seizures when used in conjunction with other medications.
• Additionally, it can be prescribed to alleviate symptoms of excessive anxiety in generalized anxiety disorder when other treatment options are unsuitable.

Indication of Nervalin 25

Indications:

• Nervalin is indicated for:
  1. Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  2. Postherpetic neuralgia (PHN)
  3. Adjunctive therapy for partial-onset seizures in patients aged 1 month and older
  4. Fibromyalgia
  5. Neuropathic pain associated with spinal cord injury
• Nervalin CR tablet is indicated for:
  1. Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  2. Postherpetic neuralgia (PHN)

Pharmacology

• Pregabalin, a structural derivative of gamma-aminobutyric acid (GABA), binds with high affinity to the alpha2-delta site in the central nervous system.
• The mechanism of action involves the modulation of voltage-gated calcium channels, resulting in anti-nociceptive and antiseizure effects.

Dosage & Administration:

• Neuropathic pain associated with DPN: Initial dose of 50 mg three times a day, maximum dose of 100 mg three times a day.
• PHN: Initial dose of 75 mg two times a day or 50 mg three times a day, maximum dose of 300 mg/day.
• Fibromyalgia: Initial dose of 75 mg two times a day, maximum dose of 450 mg/day.
• Neuropathic pain associated with spinal cord injury: Initial dose of 75 mg two times a day, maximum dose of 600 mg/day.

Interaction

• Unlikely to be involved in significant pharmacokinetic drug interactions.
• No significant interactions with food or other substances.

Contraindications

Hypersensitivity to pregabalin or any of its components.

Pregnancy & Lactation

Limited data on use during pregnancy and lactation; potential risks to fetus and nursing infants.

Precautions & Warnings

• Angioedema and hypersensitivity reactions may occur.
• Increased risk of suicidal thoughts or behavior.
• Caution is advised in patients with respiratory impairment or driving impairment.
• Withdrawal symptoms and peripheral edema may occur.
• Safety and effectiveness are not established in pediatric patients below the age of 1 month.
• Symptoms may include reduced consciousness, anxiety, confusion, agitation, seizures, and heart block.

Storage Conditions:

Store below 30°C, protected from light and moisture, and keep out of reach of children.